2020-2021 Colloquia series
The 2020-2021 MolMed Symposium was postponed due to COVID-19, then transitioned into an online colloquia "Colloquia in Translational Medicine." The list of colloquia presentations appears below.
From Discovery to the Clinic: How DavosPharma Could Assist • June 8, 2020
Keynote: "From Concept to Clinic"
- Keynote lecture: Ayyappan R. Nair – head of Discovery Biology at DavosPharma
The Pharmacology of COVID19: Emerging Drug Targets and Drug Discovery Opportunities, Part 1 • June 22, 2020
Keynote: "Discovery of SARS-CoV-2 antvirals through large scale repositioning studies"
- Keynote lecture: Sumit Chandra, Ph.D., director and professor, Immunity and Pathogenesis Program, Infectious and Inflammatory Diseases Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla
- Nucleoside analogs against the SARS-CoV-2 virus - Michael Pirrung, Ph.D., UC Riverside
- SARS-CoV2 targets from bioinformatics and structural biology - Adam Godzik, Ph.D., UC Riverside
- Targeting priming of the S-glycoprotein for possible COVID19 therapeutics - Mauricio Pellecchia, Ph.D., UC Riverside
- Targeting host factor SUMOylation for COVID-19 treatment with multiple mechanisms - Jiayu Liao, Ph.D., UC Riverside
The Pharmacology of COVID19: Emerging Drug Targets and Drug Discovery Opportunities, Part 2 • June 29, 2020
Keynote: "Targeting Coronaviral Proteases with Broad-Spectrum, Small Molecule Drugs"
- Keynote lecture: Andrew Mesecar, Purdue University
- Insights into Dynamics of Inhibitor and Ubiquitin-like Protein Binding in SARSCoV-2 Papain-like Protease - Chia-en Chang, Ph.D., UC Riverside
- Aiding the SARS-Cov-2 detection through emerging CRISPR-Cas genome editing systems - Giulia Palermo, Ph.D., UC Riverside
- Targeting SARS-Cov-2 Nsp-13 Helicase by Fragment-Based Drug Discovery - Jeff Perry, Ph.D., UC Riverside
Covalent Drugs in Oncology - Part 1 • July 27, 2020
Keynote: "The Discovery of AMG 510 (Sotorasib), a First-in-Class Covalent Inhibitor of KRAS(G12C)"
- Keynote lecture: Dr. Brian Lanman, principal scientist at Amgen
- Developing Covalent Protein Drugs via PERx - Lei Wang, PhD - professor in the Department of Pharmaceutical Chemistry from the University of California, San Francisco
- Translating Research into Commercial Potential: Resources from OTP - David Pearson, PhD
Covalent Drugs in Oncology - Part 2 • August 3, 2020
Keynote: "Activity-based proteomics - target and ligand discovery on a global scale"
- Keynote lecture: Benjamin Cravatt, Ph.D., professor and Gilula Chair of Chemical Biology, Department of Chemistry at The Scripps Research Institute
Targeted Protein Degradation with Bifunctional Molecules: how PROTACs work - Part 1 • November 30, 2020
Keynote: "Hacking protein-protein interaction networks with small molecules"
- Keynote lecture: Michelle Arkin, PhD, University of California, San Francisco
Targeted Protein Degradation with Bifunctional Molecules: how PROTACs work - Part 2 • December 15, 2020
Keynote: "Targeted Protein Degradation with Small Molecules: How PROTACs work"
- Keynote lecture: Alessio Ciulli, FRSC, PhD, professor of Chemical & Structural Biology, School of Life Sciences, University of Dundee
PROTACs Technology • January 25, 2021
Keynote: "Small Molecule Probes of the untapped Proteome: inhibitors, chaperones, degraders, and other things..."
Keynote lecture: Matthias Baud, PhD, University of Southampton