The faculty of the Center for Molecular and Translational Medicine (MolMed) cover several aspects of translational research, from the discovery and characterization of novel disease-modifying target genes to the development and application of innovative technologies to accelerate drug discovery and develop novel treatments for several human conditions.
These include neurodegenerative diseases such as amyotrophic lateral sclerosis and Alzheimer’s disease, neurodevelopmental disorders, traumatic brain injury, spinal cord injury, obesity and metabolic disorders, stroke, cancer (including prostate and breast cancer, pancreatic cancer, melanoma and certain types of leukemia), infectious diseases (including influenza, HIV, dengue, and other emerging or re-emerging infection diseases), neuro-immune disorders (including multiple sclerosis), inflammatory diseases, and other conditions.
Our faculty bring expertise in dissecting the molecular aspects of disease, including developing modern and innovative approaches that combine biophysical (nuclear magnetic resonance, isothermal titration calorimetry, X-ray crystallography etc.), biochemical (chip-based fluorescence assays, high content cell imaging, etc.), and chemical biology strategies including combinatorial approaches, fragment-based drug design, peptide mimetics, and approaches to target protein-protein interactions.